Telomere length as a biomarker of aging and diseases

As research related to healthspan and lifespan has become a hot topic, the necessity for reliable practical biomarker of aging (BoA), which can provide information about mortality morbidity risk, along with remaining life expectancy, increased. The chromosome terminus non-coding protective structure that prevents genomic instability is called telomere. continual shortening telomeres, affects their as well function, hallmark agedness. aforementioned process potential cause age-related diseases (ARDs), leading bad prognosis low survival rate, compromise health longevity. Hence, studies scrutinizing BoAs often include telomere length (TL) prospective candidate. results these suggest TL measurement only an approximate appraisal its implementation into clinical practice routine use BoA many limitations challenges. Nevertheless, measuring while determining other biomarkers be used assess biological age. This review focuses on importance telomeres in health, senescence, diseases, summarizing conclusions previous evaluating BoA.